Texas A&M Institute for Genomic Medicine is home to the world's largest collection of C57 ES Cells and Mice. To date, TIGM has provided more than 295 mouse lines and more than 3,700 ES cell lines to research community. TIGM continues to offer a variety of services to the domestic and international research communities and high-throughput screening of our ES cell library. Important scientific breakthroughs are made with both direct and indirect involvement of TIGM; more than 90 peer-reviewed papers have been published by either TIGM scientists or external researchers who utilized TIGM resources have been published. We now have more than 220 mouse lines in our repository all available at cost recovery rates. These are in addition to 170 NIH- and Wellcome-Trust-subsidized lines also available through TIGM.